Doctor Doom, Fantastic Four and Robert Downey Jr.
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A good chunk of Doomsday could focus on a clash between Avengers and X-Men with RDJ’s Doom cackling in the background, with a kidnapped Franklin by his side. The premise certainly gives the Fantastic Four a reason to breach their multiversal walls and zip over to 616 to meet the New Avengers.
Can Doctor Doom beat Thanos? It's an increasingly common question among Marvel fans, with Robert Downey, Jr.'s Doctor Doom set to inherit the title of the greatest enemy of the Avengers from Josh Brolin's Mad Titan, the almighty Thanos.