Women's Final Four national championship game pick, prediction, odds ahead of South Carolina vs Texas, UCLA vs UConn national semifinal games Friday.

CBS Sports and TNT Sports will combine to provide live coverage of all 67 games from the 2025 NCAA Tournament. Basketball competition officially tipped Tuesday night on truTV with the First Four contested in Dayton, Ohio and concludes with the NCAA Championship Game April 7 in San Antonio on CBS.

Which team will be 2025 men's college basketball national champion? What Final Four picks, odds say about Duke, Houston, Auburn, Florida's chances.

According to DraftKings, Duke (+110) has the best odds to win the title entering the Final Four. Florida (+250), Houston (+400) and Auburn (+475) round out the rest of the Final Four teams. Gambling problem? Call (877-8-HOPENY) or text HOPENY (467369).

Geno Auriemma will participate in his 24th Final Four as head coach of UConn, while UCLA is in its first-ever Women's Final Four. UCLA has been one of the great stories of the season behind star Lauren Betts, but this is UConn in the NCAA tournament.

Here’s a look at the odds to win the Final Four ahead of Saturday’s March Madness semifinals. Duke is the Final Four favorite at +100 odds at bet365 as of April 2, 2025. That price is warranted considering the talent of this Duke Blue Devils squad, but it also reflects a season’s worth of NCAA Tournament futures piling up on the Dukies.

The SportsLine Projection Model has revealed its Houston Cougars vs. Duke Blue Devils picks for the Final Four of the 2025 NCAA Tournament on Saturday